Leo Kager Selected Research

Cardiotoxicity

7/2015

Can pharmacogenomics help to improve therapy in patients with high-grade osteosarcoma?

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Leo Kager Research Topics

Disease

21	Neoplasms (Cancer) 10/2021 - 05/2003
10	Osteosarcoma (Osteogenic Sarcoma) 01/2021 - 06/2010
5	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 05/2008 - 09/2004
4	Leukemia 01/2014 - 01/2005
3	Sarcoma (Soft Tissue Sarcoma) 01/2022 - 01/2016
3	Wilms Tumor (Wilm's Tumor) 09/2021 - 09/2014
3	Necrosis 01/2020 - 11/2010
3	Neoplasm Metastasis (Metastasis) 10/2016 - 05/2003
2	Cardiomyopathies (Cardiomyopathy) 01/2021 - 01/2021
2	Rhabdoid Tumor (Rhabdoid Tumors) 11/2020 - 09/2014
1	monosomy Chromosome 7 01/2022
1	Cytopenia 01/2022
1	Neuroblastoma 09/2021
1	Pathologic Complete Response 06/2021
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 06/2021
1	Autoimmune Pancreatitis 06/2021
1	Chondrosarcoma 01/2021
1	Hearing Loss (Hearing Impairment) 01/2021
1	Growth Disorders 01/2021
1	Renal Insufficiency (Renal Failure) 01/2021
1	Viremia 12/2020
1	Lymphoma (Lymphomas) 12/2020
1	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 12/2020
1	Infectious Mononucleosis (Glandular Fever) 12/2020
1	Ewing Sarcoma (Sarcoma, Ewing) 01/2018
1	Actinomycosis 01/2018
1	Strabismus (Squint) 03/2017
1	Giant Cell Tumor of Bone 03/2017
1	Paralysis (Palsy) 03/2017
1	Diplopia (Double Vision) 03/2017
1	Cachexia 03/2017
1	Dysphonia (Spastic Dysphonia) 03/2017
1	Diamond-Blackfan Anemia (Anemia, Diamond Blackfan) 01/2017
1	Infections 10/2016
1	Infarction (Infarctions) 10/2016
1	Left Ventricular Dysfunction 10/2016
1	Hemolytic Anemia 05/2016
1	Disease Progression 07/2015
1	Cardiotoxicity 07/2015
1	Mucositis 06/2013
1	Megaloblastic Anemia 11/2012
1	Deafness (Deaf Mutism) 11/2012
1	Rare Diseases (Rare Disease) 06/2010
1	Long Term Adverse Effects 07/2006
1	Breast Neoplasms (Breast Cancer) 01/2005

Drug/Important Bio-Agent (IBA)

6	Methotrexate (Mexate)FDA LinkGeneric 10/2016 - 09/2004
5	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020 - 09/2014
4	Pharmaceutical PreparationsIBA 07/2015 - 07/2006
3	Cisplatin (Platino)FDA LinkGeneric 10/2016 - 07/2015
2	Biomarkers (Surrogate Marker)IBA 09/2021 - 10/2016
2	AnthracyclinesIBA 01/2021 - 09/2014
2	Proteins (Proteins, Gene)FDA Link 01/2014 - 01/2005
1	mesoglycanIBA 09/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 06/2021
1	eltrombopag FDA Link 06/2021
1	LigandsIBA 12/2020
1	Peptide Hydrolases (Proteases)FDA Link 01/2020
1	melflufenIBA 01/2020
1	Irinotecan (Camptosar)FDA LinkGeneric 02/2018
1	LactamsIBA 01/2018
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2018
1	Denosumab FDA Link 03/2017
1	Etoposide (VP 16)FDA LinkGeneric 10/2016
1	Ifosfamide FDA LinkGeneric 10/2016
1	Pyruvate KinaseIBA 05/2016
1	Protons (Proton)IBA 01/2016
1	Biological ProductsIBA 01/2016
1	peginterferon alfa-2b (Pegintron)FDA Link 07/2015
1	Vincristine (Oncovin)FDA LinkGeneric 09/2014
1	Dactinomycin (Actinomycin)FDA LinkGeneric 09/2014
1	Thiamine (Aneurin)FDA Link 11/2012
1	mifamurtideIBA 06/2010
1	Complementary DNA (cDNA)IBA 04/2008
1	AntimetabolitesIBA 04/2008
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2005
1	OligonucleotidesIBA 01/2005
1	Reduced Folate Carrier ProteinIBA 01/2005
1	methotrexate polyglutamateIBA 01/2005
1	purineIBA 09/2004
1	Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric 09/2004

Therapy/Procedure

16	Drug Therapy (Chemotherapy) 10/2021 - 05/2003
13	Therapeutics 06/2021 - 04/2006
4	Neoadjuvant Therapy 01/2018 - 04/2006
2	Hematopoietic Stem Cell Transplantation 01/2022 - 12/2020
2	Aftercare (After-Treatment) 01/2022 - 01/2021
2	Radiotherapy 11/2020 - 01/2016
1	Immunotherapy 09/2021
1	Adjuvant Radiotherapy 03/2017
1	Stem Cell Transplantation 01/2017
1	Heavy Ion Radiotherapy 01/2016
1	Induction Chemotherapy 07/2015
1	Adjuvant Chemotherapy 06/2010